NeOnc Technologies Holdings, Inc.

Pioneering a New Era in Brain Health Revolutionizing how we treat Central Nervous System (CNS) diseases with a groundbreaking category of drug delivery therapeutics. Read more Redefining CNS Cancer Treatment NeOnc's innovative formulations overcome the limitations of current drug delivery, leveling the playing field against Central Nervous System (CNS) cancers. Read more The Power of POH:
NeOnc's Breakthrough Discovery
At the heart of NeOnc's innovative drug delivery lies our proprietary synthesis of Perillyl Alcohol (POH), a naturally occurring compound that has demonstrated remarkable efficacy in treating patients with recurrent gliomas. Read more
We are committed to a world free from the fear of brain cancer. Our mission is to pursue innovative solutions that enhance patient care, bring hope, and extend lives. We aim to transform the standard of care for treating brain and Central Nervous System diseases through our dedication to research, close collaboration with medical professionals, and personalized care that always places patients and their families at the center of everything we do.
OUR MISSION

Breaking Through Barriers: NeOnc's Delivery Revolution

WHY NeOnc

NeOnc has developed a proprietary, patented platform technology designed to transport therapeutics directly to the brain, overcoming the limitations of the Blood-Brain Barrier (BBB). Our innovative formulations offer pharmaceutical companies a new pathway to deliver potentially more effective treatments for Central Nervous System (CNS) diseases, expanding possibilities for patients.

The Problem

The potential for greater success in treating devastating CNS diseases like Glioblastoma has long been severely limited. The primary hurdle is the persistent inability to effectively and directly deliver therapeutic agents to the brain, a challenge that has historically prevented many promising treatments from reaching their full potential.

Our Solution

Our proprietary approaches and patented technologies are delivering new therapies for brain cancers. We also facilitate the transport of established and new therapeutics across the blood-brain barrier, significantly improving their efficacy for treating a wide range of brain diseases.

The Potential

By regulating tumor cell growth and providing a powerful transport mechanism for therapeutics, we plan to equip doctors and healthcare professionals with the tools to deliver significantly better outcomes for their patients.

Our Latest Research & Study

Latest Studies

NeOnc maintains an aggressive regimen of research and study into our therapeutic delivery and formulations. This commitment ensures our continued ability to impact the treatment of CNS-based diseases.

NEO100 Research Shows Impact On Recurrent Grade 4 Astrocytoma

Patients with grade 4 gliomas, particularly those experiencing recurrence, need better treatment options. Researchers are developing NEO100, a clinical-grade version of perillyl alcohol, a natural compound, to be delivered intranasally…

NEO100 Intranasal Delivery Technology Shows Promise for Better Therapeutic Results.

This paper discusses the need for better treatment options for patients suffering from astrocytoma and glioblastoma (GBM), the two most frequently diagnosed primary brain tumors. In addition, secondary brain cancers…

Study Shows NEO400 Has Therapeutic Effect On UV-Induced Skin Damage

A study conducted by NeOnc Technologies Holdings and published in the Wiley Online Research Library examined the effects of NeOnc’s NEO400 formulation for treating skin damage caused by prolonged ultraviolet…

NEO100 Enhances Entry And Therapeutic Activity Of Chimeric Antigen Receptor T Cells

In an article published in the Journal of Neurosurgery website, the study results were posted on Neonc Technologies Holdings’ recent animal study looking at the efficacy of using the NEO100…

Transfemoral Injection of NEO100 Provides Potential for Delivery of Therapeutics to the Brain

In an article published on the Oncotarget.com website, the use of transfemoral injection of NEO100 to provide entry for therapeutics into the brain is explored. The paper provides an overview…

Postsurgical Biopsy Shows Viability of NEO100 Intranasal Delivery

In a recent case trial follow up of a patient with a recurring glioblastoma (GBM) tumor who had been undergoing NEO100 intranasal treatment, a postsurgical biopsy of the tumor showed…

NeOnc's NEO100 is changing lives

NTHI
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Investing in the Future of CNS Therapeutics

Stock Information

Our commitment to advancing brain and Central Nervous System therapeutics drives our mission to create enduring value for patients and stakeholders alike. We believe our relentless pursuit of innovative solutions to transform the standard of care is a catalyst for long-term growth. Through a focused dedication to research, strategic collaboration with leading medical professionals, and a patient-centric approach, we are positioned to deliver impactful treatments and robust returns. Our groundbreaking work is not only about bringing hope and extending lives, it’s about building a sustainable and valuable enterprise for the future.

Latest Press Releases

FROM THE PRESS ROOM

NeOnc Technologies (Nasdaq: NTHI) to Host Investor Conference Call to Present Data Updates from Ongoing NEO100-1 Phase 1/2a Clinical Trial and Compassionate Use Program

CALABASAS, Calif., Nov. 07, 2025 (GLOBE NEWSWIRE) — NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a clinical-stage biopharmaceutical company developing novel brain-penetrant therapeutics for patients with malignant brain…

NeOnc Technologies Appoints Amir Heshmatpour as Chief Executive Officer to Drive Next Phase of Clinical and Corporate Growth

CALABASAS, Calif., Nov. 04, 2025 (GLOBE NEWSWIRE) — NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a multi-Phase 2 clinical-stage biopharmaceutical company pioneering therapies for central nervous system (CNS)…

His Highness Sheikh Nahyan bin Zayed Al Nahyan Assumes Executive Chairmanship of NeOnc Technologies’ Subsidiary, NuroMENA, Pioneering UAE-US Partnership in Brain Cancer Treatment

CALABASAS, Calif. and ABU DHABI, United Arab Emirates, Oct. 28, 2025 (GLOBE NEWSWIRE) — NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a multi-Phase 2 clinical-stage biopharmaceutical company pioneering…

NeOnc Technologies’ Subsidiary, NuroMENA, Signs Master Services Agreement with M42’s IROS and Expands Board of Directors

CALABASAS, Calif. and ABU DHABI, United Arab Emirates, Oct. 09, 2025 (GLOBE NEWSWIRE) — NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a multi-Phase 2 clinical-stage biopharmaceutical company pioneering therapies for…

NeOnc Technologies and Quazar Investment Set to Close $50 Million Strategic Partnership by October 23rd Following Final UAE Tax Approvals

CALABASAS, Calif., Oct. 06, 2025 (GLOBE NEWSWIRE) — NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a multi-Phase 2 clinical-stage biopharmaceutical company pioneering therapies for central nervous system (CNS)…

NeOnc Technologies Appoints Dr. David M. Ashley, Director of The Preston Robert Tisch Brain Tumor Center at Duke, to Scientific Advisory Board

CALABASAS, Calif., Oct. 02, 2025 (GLOBE NEWSWIRE) — NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a multi-Phase 2 clinical-stage biopharmaceutical company pioneering therapies for central nervous system (CNS) cancers, today…

Latest News & Insights

FROM THE NEWS ROOM

NeOnc Technologies: From Survival Mode To Expansion Mode

Summary NeOnc Technologies Holdings is a micro-cap biotech focused on innovative brain cancer treatments, NEO100 and NEO212, both in early clinical trials. NTHI’s financials are challenging, with no revenue, rising…

Building Biotech Excellence: The Growth Strategy Behind NeOnc Technologies’ Vision

NeOnc Executive Team: (l-r) Pat Walters, Dr. Thomas Chen, Amir Heshmatpour, Keithly A. Garnett Publication Date: March 13, 2025 Published By: Venture Beat Article  Link: https://venturebeat.com/business/building-biotech-excellence-the-growth-strategy-behind-neonc-technologies-vision/ In his years as…

USC-licensed Startup NeOnc Technologies Celebrates NASDAQ Listing

Publication Date: March 27, 2025 Published By: Healthcare Executive Article  Link: https://www.healthcareexecutive.in/blog/usc-licensed-startup On Wednesday, a USC-licensed startup biomedical company and Keck Medicine of USC neurosurgeon focused on treating brain cancer…

NASDAQ’S Opening Bell Will Ring For USC Research Startup

Publication Date: March 25, 2025 Published By: USC Today Article Link: https://today.usc.edu/nasdaqs-opening-bell-will-ring-for-usc-research-startup/ A USC-licensed startup biomedical company and a Keck Medicine of USC neurosurgeon focused on treating brain cancer are…

Pioneering a New Era in Brain Cancer Treatment with NASDAQ Listing

Publication Date: March 25, 2025 Published By: USC Today Article  Link: https://healthcare360magazine.com/nasdaq-visionaries-neonc-technologies/ The landscape of healthcare is in a state of perpetual evolution, driven by relentless innovation and a desire…

Healthcare Entrepreneurs Express Hope, Concern Over RFK Jr. Confirmation

Publication Date: March 14, 2025 Published By: Wall Street Journal Article  Link: https://www.wsj.com/articles/healthcare-entrepreneurs-express-hope-concern-over-rfk-jr-confirmation-a0548927 FDA Head Robert F. Kennedy Jr. While several entrepreneurs expressed optimism, some said they were concerned vaccines…